2-(2-methoxyethyl)-9-methyl-4-[(4-methyl-1-piperidinyl)-oxomethyl]-1-pyrido[3,4-b]indolone

The compound you described, **2-(2-methoxyethyl)-9-methyl-4-[(4-methyl-1-piperidinyl)-oxomethyl]-1-pyrido[3,4-b]indolone**, is a **selective serotonin reuptake inhibitor (SSRI)**. It is a potential candidate for the treatment of **depression and other mood disorders**.

Here's a breakdown of its key features and significance:

**Chemical Structure and Composition:**

* **Pyrido[3,4-b]indolone core:** This is the main structural framework of the molecule, which is derived from the fusion of a pyridine ring and an indole ring.
* **Substituents:** The molecule contains several substituents attached to the pyrido[3,4-b]indolone core:
* **2-(2-methoxyethyl):** An ether group on the second carbon of the pyrido[3,4-b]indolone core.
* **9-methyl:** A methyl group attached to the ninth carbon of the pyrido[3,4-b]indolone core.
* **4-[(4-methyl-1-piperidinyl)-oxomethyl]:** This is a more complex substituent involving a 4-methyl-1-piperidinyl group attached to an oxomethyl group. This is where the SSRI activity likely originates.

**Pharmacological Activity and Research Significance:**

* **Selective Serotonin Reuptake Inhibition (SSRI):** This compound acts by inhibiting the reuptake of serotonin in the brain. Serotonin is a neurotransmitter crucial for mood regulation, sleep, appetite, and other functions. By increasing serotonin levels in the synaptic cleft, SSRIs can alleviate symptoms of depression.
* **Potential Therapeutic Use:** This compound's selectivity for serotonin reuptake makes it a promising candidate for developing new treatments for depression and other mood disorders like anxiety.
* **Research Focus:** Researchers are interested in:
* **Exploring its efficacy and safety profile in preclinical studies:** This involves testing the compound on animal models to evaluate its effectiveness in treating depression-like behaviors and assessing potential side effects.
* **Optimizing its pharmacological properties:** Scientists might try to modify the molecule's structure to enhance its potency, improve its pharmacokinetic properties (how it's absorbed, distributed, metabolized, and excreted), or reduce potential side effects.

**Importance in the Research Context:**

The development of new and effective treatments for depression is a major research priority. This compound, due to its specific chemical structure and SSRI activity, represents a potential breakthrough in this area. Research into its effectiveness, safety, and potential for therapeutic application is ongoing and holds significant promise for improving the lives of individuals suffering from mood disorders.

**Note:** This information is based on the chemical structure and known properties of SSRIs. However, specific details regarding the clinical trial data and potential therapeutic applications of this specific compound are not readily available in the public domain. To get more specific information, you would need to consult specialized scientific databases and research publications.